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Photosensitizer Activation Drives Apoptosis by Interorganellar Ca(2+) Transfer and Superoxide Production in Bystander Cancer Cells

In cells, photosensitizer (PS) activation by visible light irradiation triggers reactive oxygen species (ROS) formation, followed by a cascade of cellular responses involving calcium (Ca(2+)) and other second messengers, resulting in cell demise. Cytotoxic effects spread to nearby cells not exposed...

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Detalles Bibliográficos
Autores principales: Nardin, Chiara, Peres, Chiara, Mazzarda, Flavia, Ziraldo, Gaia, Salvatore, Anna Maria, Mammano, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829494/
https://www.ncbi.nlm.nih.gov/pubmed/31569545
http://dx.doi.org/10.3390/cells8101175