Cargando…

Parameter Optimization in High-Throughput Testing for Structural Materials

High-throughput screenings are established evaluation methods in the development of functional materials and pharmaceutical active ingredients. The transfer of this approach to the development of structural materials requires extensive adaptations. In addition to the investigation of new test proced...

Descripción completa

Detalles Bibliográficos
Autores principales: Bader, Alexander, Toenjes, Anastasiya, Wielki, Nicole, Mändle, Andreas, Onken, Ann-Kathrin, von Hehl, Axel, Meyer, Daniel, Brannath, Werner, Tracht, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829500/
https://www.ncbi.nlm.nih.gov/pubmed/31640170
http://dx.doi.org/10.3390/ma12203439
_version_ 1783465570819112960
author Bader, Alexander
Toenjes, Anastasiya
Wielki, Nicole
Mändle, Andreas
Onken, Ann-Kathrin
von Hehl, Axel
Meyer, Daniel
Brannath, Werner
Tracht, Kirsten
author_facet Bader, Alexander
Toenjes, Anastasiya
Wielki, Nicole
Mändle, Andreas
Onken, Ann-Kathrin
von Hehl, Axel
Meyer, Daniel
Brannath, Werner
Tracht, Kirsten
author_sort Bader, Alexander
collection PubMed
description High-throughput screenings are established evaluation methods in the development of functional materials and pharmaceutical active ingredients. The transfer of this approach to the development of structural materials requires extensive adaptations. In addition to the investigation of new test procedures for the determination of material properties and the treatment of metallic materials, the design of experiments is a research focus. Based on given descriptor target values, the statistical design of experiments determines investigations and treatments for the investigation of these materials. In this context, process parameters also have to be determined, as these have a major influence on the later material properties, especially during the treatment of samples. In this article, a method is presented which determines the process parameters iteratively. The validation of the calculated process parameters takes place based on differential scanning calorimetry used as the furnace for the heat treatment of small batches and particle-oriented peening as the characterization method.
format Online
Article
Text
id pubmed-6829500
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-68295002019-11-18 Parameter Optimization in High-Throughput Testing for Structural Materials Bader, Alexander Toenjes, Anastasiya Wielki, Nicole Mändle, Andreas Onken, Ann-Kathrin von Hehl, Axel Meyer, Daniel Brannath, Werner Tracht, Kirsten Materials (Basel) Article High-throughput screenings are established evaluation methods in the development of functional materials and pharmaceutical active ingredients. The transfer of this approach to the development of structural materials requires extensive adaptations. In addition to the investigation of new test procedures for the determination of material properties and the treatment of metallic materials, the design of experiments is a research focus. Based on given descriptor target values, the statistical design of experiments determines investigations and treatments for the investigation of these materials. In this context, process parameters also have to be determined, as these have a major influence on the later material properties, especially during the treatment of samples. In this article, a method is presented which determines the process parameters iteratively. The validation of the calculated process parameters takes place based on differential scanning calorimetry used as the furnace for the heat treatment of small batches and particle-oriented peening as the characterization method. MDPI 2019-10-21 /pmc/articles/PMC6829500/ /pubmed/31640170 http://dx.doi.org/10.3390/ma12203439 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bader, Alexander
Toenjes, Anastasiya
Wielki, Nicole
Mändle, Andreas
Onken, Ann-Kathrin
von Hehl, Axel
Meyer, Daniel
Brannath, Werner
Tracht, Kirsten
Parameter Optimization in High-Throughput Testing for Structural Materials
title Parameter Optimization in High-Throughput Testing for Structural Materials
title_full Parameter Optimization in High-Throughput Testing for Structural Materials
title_fullStr Parameter Optimization in High-Throughput Testing for Structural Materials
title_full_unstemmed Parameter Optimization in High-Throughput Testing for Structural Materials
title_short Parameter Optimization in High-Throughput Testing for Structural Materials
title_sort parameter optimization in high-throughput testing for structural materials
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829500/
https://www.ncbi.nlm.nih.gov/pubmed/31640170
http://dx.doi.org/10.3390/ma12203439
work_keys_str_mv AT baderalexander parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT toenjesanastasiya parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT wielkinicole parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT mandleandreas parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT onkenannkathrin parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT vonhehlaxel parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT meyerdaniel parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT brannathwerner parameteroptimizationinhighthroughputtestingforstructuralmaterials
AT trachtkirsten parameteroptimizationinhighthroughputtestingforstructuralmaterials