Inhibition of Dephosphorylation of Dolichyl Diphosphate Alters the Synthesis of Dolichol and Hinders Protein N-Glycosylation and Morphological Transitions in Candida albicans

The essential role of dolichyl phosphate (DolP) as a carbohydrate carrier during protein N-glycosylation is well established. The cellular pool of DolP is derived from de novo synthesis in the dolichol branch of the mevalonate pathway and from recycling of DolPP after each cycle of N-glycosylation,...

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Detalles Bibliográficos
Autores principales: Janik, Anna, Niewiadomska, Monika, Perlińska-Lenart, Urszula, Lenart, Jacek, Kołakowski, Damian, Skorupińska-Tudek, Karolina, Swiezewska, Ewa, Kruszewska, Joanna S., Palamarczyk, Grażyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829516/
https://www.ncbi.nlm.nih.gov/pubmed/31614738
http://dx.doi.org/10.3390/ijms20205067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829516/
https://www.ncbi.nlm.nih.gov/pubmed/31614738
http://dx.doi.org/10.3390/ijms20205067

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