Mutations in NDUFS1 Cause Metabolic Reprogramming and Disruption of the Electron Transfer

Complex I (CI) is the first enzyme of the mitochondrial respiratory chain and couples the electron transfer with proton pumping. Mutations in genes encoding CI subunits can frequently cause inborn metabolic errors. We applied proteome and metabolome profiling of patient-derived cells harboring patho...

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Detalles Bibliográficos
Autores principales: Ni, Yang, Hagras, Muhammad A., Konstantopoulou, Vassiliki, Mayr, Johannes A., Stuchebrukhov, Alexei A., Meierhofer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829531/
https://www.ncbi.nlm.nih.gov/pubmed/31557978
http://dx.doi.org/10.3390/cells8101149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829531/
https://www.ncbi.nlm.nih.gov/pubmed/31557978
http://dx.doi.org/10.3390/cells8101149

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