Low temperature traps myosin motors of mammalian muscle in a refractory state that prevents activation

Myosin motors in the thick filament of resting striated (skeletal and cardiac) muscle are trapped in an OFF state, in which the motors are packed in helical tracks on the filament surface, inhibiting their interactions with actin and utilization of ATP. To investigate the structural changes induced...

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Detalles Bibliográficos
Autores principales: Caremani, Marco, Brunello, Elisabetta, Linari, Marco, Fusi, Luca, Irving, Thomas C., Gore, David, Piazzesi, Gabriella, Irving, Malcolm, Lombardi, Vincenzo, Reconditi, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829559/
https://www.ncbi.nlm.nih.gov/pubmed/31554652
http://dx.doi.org/10.1085/jgp.201912424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829559/
https://www.ncbi.nlm.nih.gov/pubmed/31554652
http://dx.doi.org/10.1085/jgp.201912424

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