B cell dissemination patterns during the germinal center reaction revealed by whole-organ imaging

Germinal centers (GCs) are sites wherein B cells proliferate and mutate their immunoglobulins in the dark zone (DZ), followed by affinity-based selection in the light zone (LZ). Here, we mapped the location of single B cells in the context of intact lymph nodes (LNs) throughout the GC response, and...

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Detalles Bibliográficos
Autores principales: Stoler-Barak, Liat, Biram, Adi, Davidzohn, Natalia, Addadi, Yoseph, Golani, Ofra, Shulman, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829594/
https://www.ncbi.nlm.nih.gov/pubmed/31492809
http://dx.doi.org/10.1084/jem.20190789

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