The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function

The inner mucus layer (IML) is a critical barrier that protects the colonic epithelium from luminal threats and inflammatory bowel disease. Innate immune signaling is thought to regulate IML formation via goblet cell Nlrp6 inflammasome activity that controls secretion of the mucus structural compone...

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Detalles Bibliográficos
Autores principales: Volk, Joana K., Nyström, Elisabeth E.L., van der Post, Sjoerd, Abad, Beatriz M., Schroeder, Bjoern O., Johansson, Åsa, Svensson, Frida, Jäverfelt, Sofia, Johansson, Malin E.V., Hansson, Gunnar C., Birchenough, George M.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829596/
https://www.ncbi.nlm.nih.gov/pubmed/31420376
http://dx.doi.org/10.1084/jem.20190679

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