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TGFβ signaling in germinal center B cells promotes the transition from light zone to dark zone

B cells in germinal centers (GCs) cycle between light zone (LZ) and dark zone (DZ). The cues in the GC microenvironment that regulate the transition from LZ to DZ have not been well characterized. In Peyer’s patches (PPs), transforming growth factor-β (TGFβ) promotes IgA induction in activated B cel...

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Detalles Bibliográficos
Autores principales: Albright, Anne R., Kabat, Juraj, Li, Moyi, Raso, Fiona, Reboldi, Andrea, Muppidi, Jagan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829600/
https://www.ncbi.nlm.nih.gov/pubmed/31506281
http://dx.doi.org/10.1084/jem.20181868