Death by microglia

The roles of microglia and ApoE in tauopathies, such as Alzheimer’s disease, remain elusive. In this issue, Shi et al. (https://doi.org/10.1084/jem.20190980) demonstrate that microglia-mediated innate immunity collaborates with ApoE to drive neurodegeneration and disease progression in a mouse model...

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Detalles Bibliográficos
Autores principales: Kemal, Shahrnaz, Vassar, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
News
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829604/
https://www.ncbi.nlm.nih.gov/pubmed/31645368
http://dx.doi.org/10.1084/jem.20191536
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author Kemal, Shahrnaz
Vassar, Robert
author_facet Kemal, Shahrnaz
Vassar, Robert
author_sort Kemal, Shahrnaz
collection PubMed
description The roles of microglia and ApoE in tauopathies, such as Alzheimer’s disease, remain elusive. In this issue, Shi et al. (https://doi.org/10.1084/jem.20190980) demonstrate that microglia-mediated innate immunity collaborates with ApoE to drive neurodegeneration and disease progression in a mouse model of tauopathy.
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spelling pubmed-68296042020-05-04 Death by microglia Kemal, Shahrnaz Vassar, Robert J Exp Med News The roles of microglia and ApoE in tauopathies, such as Alzheimer’s disease, remain elusive. In this issue, Shi et al. (https://doi.org/10.1084/jem.20190980) demonstrate that microglia-mediated innate immunity collaborates with ApoE to drive neurodegeneration and disease progression in a mouse model of tauopathy. Rockefeller University Press 2019-11-04 2019-10-23 /pmc/articles/PMC6829604/ /pubmed/31645368 http://dx.doi.org/10.1084/jem.20191536 Text en © 2019 Kemal and Vassar http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle News
Kemal, Shahrnaz
Vassar, Robert
Death by microglia
title Death by microglia
title_full Death by microglia
title_fullStr Death by microglia
title_full_unstemmed Death by microglia
title_short Death by microglia
title_sort death by microglia
topic News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829604/
https://www.ncbi.nlm.nih.gov/pubmed/31645368
http://dx.doi.org/10.1084/jem.20191536
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