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IL-2 Therapy Diminishes Renal Inflammation and the Activity of Kidney-Infiltrating CD4+ T Cells in Murine Lupus Nephritis
An acquired deficiency of interleukin-2 (IL-2) and related disturbances in regulatory T cell (Treg) homeostasis play an important role in the pathogenesis of systemic lupus erythematosus (SLE). Low-dose IL-2 therapy was shown to restore Treg homeostasis in patients with active SLE and its clinical e...
Autores principales: | Rose, Angelika, von Spee-Mayer, Caroline, Kloke, Lutz, Wu, Kaiyin, Kühl, Anja, Enghard, Philipp, Burmester, Gerd-Rüdiger, Riemekasten, Gabriela, Humrich, Jens Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829607/ https://www.ncbi.nlm.nih.gov/pubmed/31614462 http://dx.doi.org/10.3390/cells8101234 |
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