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Seipin negatively regulates sphingolipid production at the ER–LD contact site
Seipin is known for its critical role in controlling lipid droplet (LD) assembly at the LD-forming subdomain of the endoplasmic reticulum (ER). Here, we identified a new function of seipin as a negative regulator for sphingolipid production. We show that yeast cells lacking seipin displayed altered...
Autores principales: | Su, Wei-Cheng, Lin, Yi-Hsiu, Pagac, Martin, Wang, Chao-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829658/ https://www.ncbi.nlm.nih.gov/pubmed/31594806 http://dx.doi.org/10.1083/jcb.201902072 |
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