SGK phosphorylates Cdc25 and Myt1 to trigger cyclin B–Cdk1 activation at the meiotic G2/M transition

The kinase cyclin B–Cdk1 complex is a master regulator of M-phase in both mitosis and meiosis. At the G2/M transition, cyclin B–Cdk1 activation is initiated by a trigger that reverses the balance of activities between Cdc25 and Wee1/Myt1 and is further accelerated by autoregulatory loops. In somatic...

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Detalles Bibliográficos
Autores principales: Hiraoka, Daisaku, Hosoda, Enako, Chiba, Kazuyoshi, Kishimoto, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829662/
https://www.ncbi.nlm.nih.gov/pubmed/31537708
http://dx.doi.org/10.1083/jcb.201812122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829662/
https://www.ncbi.nlm.nih.gov/pubmed/31537708
http://dx.doi.org/10.1083/jcb.201812122

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