Multiple giant cell formation – A consequence of type II pyrethroid intoxication

Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthr...

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Detalles Bibliográficos
Autores principales: Bhushan, Brijender, Saxena, Prabhu Narain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2018
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829680/
https://www.ncbi.nlm.nih.gov/pubmed/31719789
http://dx.doi.org/10.2478/intox-2018-0014
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author Bhushan, Brijender
Saxena, Prabhu Narain
author_facet Bhushan, Brijender
Saxena, Prabhu Narain
author_sort Bhushan, Brijender
collection PubMed
description Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthrin. Histopathological examination was done for this purpose and the results revealed the formation of giant cells and polyploidy condition following intoxication of these experimental compounds with Beta-cyfluthrin, with an edge over, and Cypermethrin, probably due to structural differences.
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spelling pubmed-68296802019-11-12 Multiple giant cell formation – A consequence of type II pyrethroid intoxication Bhushan, Brijender Saxena, Prabhu Narain Interdiscip Toxicol Short Communication Pesticides are the main remedy for pest eradication, but their use has been found to be harmful also to various non-target organisms. In this study, giant cell formation was observed in hepatocytes of experimental albino rats following two type II pyrethroid pesticdes, Cypermethrin and Beta-cyfluthrin. Histopathological examination was done for this purpose and the results revealed the formation of giant cells and polyploidy condition following intoxication of these experimental compounds with Beta-cyfluthrin, with an edge over, and Cypermethrin, probably due to structural differences. Slovak Toxicology Society SETOX 2018-08 2019-03-02 /pmc/articles/PMC6829680/ /pubmed/31719789 http://dx.doi.org/10.2478/intox-2018-0014 Text en Copyright © 2018 SETOX & Institute of Experimental Pharmacology and Toxicology, SASc. https://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. (CC BY-NC-ND 4.0)
spellingShingle Short Communication
Bhushan, Brijender
Saxena, Prabhu Narain
Multiple giant cell formation – A consequence of type II pyrethroid intoxication
title Multiple giant cell formation – A consequence of type II pyrethroid intoxication
title_full Multiple giant cell formation – A consequence of type II pyrethroid intoxication
title_fullStr Multiple giant cell formation – A consequence of type II pyrethroid intoxication
title_full_unstemmed Multiple giant cell formation – A consequence of type II pyrethroid intoxication
title_short Multiple giant cell formation – A consequence of type II pyrethroid intoxication
title_sort multiple giant cell formation – a consequence of type ii pyrethroid intoxication
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829680/
https://www.ncbi.nlm.nih.gov/pubmed/31719789
http://dx.doi.org/10.2478/intox-2018-0014
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