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Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India
Washing soda has been identified as a precarious contaminant of the freshwater ponds and lakes, the natural habitat of Eunapius carteri. Treatment of sublethal concentrations of washing soda for 384 hours exhibited a significant decrease in the densities of blast like cells, small and large amoebocy...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Slovak Toxicology Society SETOX
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829681/ https://www.ncbi.nlm.nih.gov/pubmed/31719787 http://dx.doi.org/10.2478/intox-2018-0012 |
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author | Mukherjee, Soumalya Ray, Mitali Ray, Sajal |
author_facet | Mukherjee, Soumalya Ray, Mitali Ray, Sajal |
author_sort | Mukherjee, Soumalya |
collection | PubMed |
description | Washing soda has been identified as a precarious contaminant of the freshwater ponds and lakes, the natural habitat of Eunapius carteri. Treatment of sublethal concentrations of washing soda for 384 hours exhibited a significant decrease in the densities of blast like cells, small and large amoebocytes. The percentage occurrence of granular cells and archaeocytes yielded a marked increase against the experimental concentrations of washing soda. Washing soda mediated alterations in the differential cell densities of E. carteri indicative of a state of physiological stress and an undesirable shift in the cellular homeostasis of the organism distributed in polluted environment. Experimental exposure of washing soda yielded a significant increase in the cellular dimensions of large amoebocytes and archaeocytes. Prolonged treatment with washing soda presented a gross reduction in nonself surface adhesion efficacy of E. carteri cells. Experimental concentrations of washing soda resulted in a dose dependent increment in the frequencies of binucleation and micronucleation in the cells of E. carteri. The data were indicative of a high level of genotoxicity of washing soda in E. carteri. The present investigation provides an important information base in understanding the toxin induced chemical stress on the archaic immune defense of a primitive urmetazoa. |
format | Online Article Text |
id | pubmed-6829681 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Slovak Toxicology Society SETOX |
record_format | MEDLINE/PubMed |
spelling | pubmed-68296812019-11-12 Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India Mukherjee, Soumalya Ray, Mitali Ray, Sajal Interdiscip Toxicol Original Article Washing soda has been identified as a precarious contaminant of the freshwater ponds and lakes, the natural habitat of Eunapius carteri. Treatment of sublethal concentrations of washing soda for 384 hours exhibited a significant decrease in the densities of blast like cells, small and large amoebocytes. The percentage occurrence of granular cells and archaeocytes yielded a marked increase against the experimental concentrations of washing soda. Washing soda mediated alterations in the differential cell densities of E. carteri indicative of a state of physiological stress and an undesirable shift in the cellular homeostasis of the organism distributed in polluted environment. Experimental exposure of washing soda yielded a significant increase in the cellular dimensions of large amoebocytes and archaeocytes. Prolonged treatment with washing soda presented a gross reduction in nonself surface adhesion efficacy of E. carteri cells. Experimental concentrations of washing soda resulted in a dose dependent increment in the frequencies of binucleation and micronucleation in the cells of E. carteri. The data were indicative of a high level of genotoxicity of washing soda in E. carteri. The present investigation provides an important information base in understanding the toxin induced chemical stress on the archaic immune defense of a primitive urmetazoa. Slovak Toxicology Society SETOX 2018-08 2019-03-02 /pmc/articles/PMC6829681/ /pubmed/31719787 http://dx.doi.org/10.2478/intox-2018-0012 Text en Copyright © 2018 SETOX & Institute of Experimental Pharmacology and Toxicology, SASc. https://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. (CC BY-NC-ND 4.0) |
spellingShingle | Original Article Mukherjee, Soumalya Ray, Mitali Ray, Sajal Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India |
title | Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India |
title_full | Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India |
title_fullStr | Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India |
title_full_unstemmed | Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India |
title_short | Washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of India |
title_sort | washing soda induced alteration of the differential cell count, nonself surface adhesion efficacy and nuclear morphology of the polyphenotypic cells of a freshwater sponge of india |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829681/ https://www.ncbi.nlm.nih.gov/pubmed/31719787 http://dx.doi.org/10.2478/intox-2018-0012 |
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