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Antidotal effects of thymoquinone against neurotoxic agents

Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ again...

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Detalles Bibliográficos
Autores principales: Sanati, Ali Rajabpour, Farkhondeh, Tahereh, Samarghandian, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829686/
https://www.ncbi.nlm.nih.gov/pubmed/31719783
http://dx.doi.org/10.2478/intox-2018-0008
Descripción
Sumario:Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this reason, the literature from 1998 to 2017 regarding the protective effects of TQ against neurotoxic agents and their involvement mechanisms has been studied. The present review suggests the protective effects of TQ against neurotoxic agents in experimental models. More clinical trial studies are however needed to confirm the antidotal effects of TQ in human intoxication.