Antidotal effects of thymoquinone against neurotoxic agents

Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ again...

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Detalles Bibliográficos
Autores principales: Sanati, Ali Rajabpour, Farkhondeh, Tahereh, Samarghandian, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829686/
https://www.ncbi.nlm.nih.gov/pubmed/31719783
http://dx.doi.org/10.2478/intox-2018-0008
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author Sanati, Ali Rajabpour
Farkhondeh, Tahereh
Samarghandian, Saeed
author_facet Sanati, Ali Rajabpour
Farkhondeh, Tahereh
Samarghandian, Saeed
author_sort Sanati, Ali Rajabpour
collection PubMed
description Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this reason, the literature from 1998 to 2017 regarding the protective effects of TQ against neurotoxic agents and their involvement mechanisms has been studied. The present review suggests the protective effects of TQ against neurotoxic agents in experimental models. More clinical trial studies are however needed to confirm the antidotal effects of TQ in human intoxication.
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spelling pubmed-68296862019-11-12 Antidotal effects of thymoquinone against neurotoxic agents Sanati, Ali Rajabpour Farkhondeh, Tahereh Samarghandian, Saeed Interdiscip Toxicol Review Article Several plants which contain the active component thymoquinone (TQ) have been traditionally used in herbal medicine to treat various diseases. Several studies indicated the protective effects of TQ against neurotoxic agents. The present study was aimed to highlight the protective effects of TQ against neurotoxic agents. For this reason, the literature from 1998 to 2017 regarding the protective effects of TQ against neurotoxic agents and their involvement mechanisms has been studied. The present review suggests the protective effects of TQ against neurotoxic agents in experimental models. More clinical trial studies are however needed to confirm the antidotal effects of TQ in human intoxication. Slovak Toxicology Society SETOX 2018-08 2019-03-02 /pmc/articles/PMC6829686/ /pubmed/31719783 http://dx.doi.org/10.2478/intox-2018-0008 Text en Copyright © 2018 SETOX & Institute of Experimental Pharmacology and Toxicology, SASc. https://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. (CC BY-NC-ND 4.0)
spellingShingle Review Article
Sanati, Ali Rajabpour
Farkhondeh, Tahereh
Samarghandian, Saeed
Antidotal effects of thymoquinone against neurotoxic agents
title Antidotal effects of thymoquinone against neurotoxic agents
title_full Antidotal effects of thymoquinone against neurotoxic agents
title_fullStr Antidotal effects of thymoquinone against neurotoxic agents
title_full_unstemmed Antidotal effects of thymoquinone against neurotoxic agents
title_short Antidotal effects of thymoquinone against neurotoxic agents
title_sort antidotal effects of thymoquinone against neurotoxic agents
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829686/
https://www.ncbi.nlm.nih.gov/pubmed/31719783
http://dx.doi.org/10.2478/intox-2018-0008
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