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Robust, Long-Term Culture of Endoderm-Derived Hepatic Organoids for Disease Modeling
Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments. These applications are, however, limited in their capacity to generate functional hepatocytes in a reproducible and efficient manner. Here, we generated and charac...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829764/ https://www.ncbi.nlm.nih.gov/pubmed/31522975 http://dx.doi.org/10.1016/j.stemcr.2019.08.007 |