Cox regression increases power to detect genotype-phenotype associations in genomic studies using the electronic health record

BACKGROUND: The growth of DNA biobanks linked to data from electronic health records (EHRs) has enabled the discovery of numerous associations between genomic variants and clinical phenotypes. Nonetheless, although clinical data are generally longitudinal, standard approaches for detecting genotype-...

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Detalles Bibliográficos
Autores principales: Hughey, Jacob J., Rhoades, Seth D., Fu, Darwin Y., Bastarache, Lisa, Denny, Joshua C., Chen, Qingxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829851/
https://www.ncbi.nlm.nih.gov/pubmed/31684865
http://dx.doi.org/10.1186/s12864-019-6192-1

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