The S100A4 Transcriptional Inhibitor Niclosamide Reduces Pro-Inflammatory and Migratory Phenotypes of Microglia: Implications for Amyotrophic Lateral Sclerosis

S100A4, belonging to a large multifunctional S100 protein family, is a Ca(2+)-binding protein with a significant role in stimulating the motility of cancer and immune cells, as well as in promoting pro-inflammatory properties in different cell types. In the CNS, there is limited information concerni...

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Detalles Bibliográficos
Autores principales: Serrano, Alessia, Apolloni, Savina, Rossi, Simona, Lattante, Serena, Sabatelli, Mario, Peric, Mina, Andjus, Pavle, Michetti, Fabrizio, Carrì, Maria Teresa, Cozzolino, Mauro, D’Ambrosi, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829868/
https://www.ncbi.nlm.nih.gov/pubmed/31623154
http://dx.doi.org/10.3390/cells8101261

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