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Prime-pull vaccination with a plant-derived virus-like particle influenza vaccine elicits a broad immune response and protects aged mice from death and frailty after challenge

BACKGROUND: Administered intramuscularly (IM), plant-derived, virus-like-particle (VLP) vaccines based on the influenza hemagglutinin (HA) protein elicit both humoral and cellular responses that can protect aged mice from lethal challenge. Unlike split virus vaccines, VLPs can be administered by dif...

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Detalles Bibliográficos
Autores principales:	Hodgins, Breanna, Pillet, Stephane, Landry, Nathalie, Ward, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829930/ https://www.ncbi.nlm.nih.gov/pubmed/31700523 http://dx.doi.org/10.1186/s12979-019-0167-6

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