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Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling

BACKGROUND: Steatosis is an important clinical manifestation associated with chronic hepatitis C virus (HCV) infection. AMP-activated protein kinase (AMPK), a major mediator of lipid metabolism, regulates HCV-associated hepatic steatosis, but the underlying mechanisms remain obscure. Here we investi...

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Detalles Bibliográficos
Autores principales:	Meng, Ziyu, Liu, Qiang, Sun, Fujun, Qiao, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829953/ https://www.ncbi.nlm.nih.gov/pubmed/31684957 http://dx.doi.org/10.1186/s12944-019-1136-y

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