Cargando…

Alopecia Areata Treated with Oral Azathioprine: A Case Series

Alopecia areata is commonly encountered non scarring alopecia with clinical presentations ranging from localised bald patches to extensive involvement. Clinical course is variable ranging from self limiting disease to chronic relapsing and recalcitrant disease. Topical and oral corticosteroids; none...

Descripción completa

Detalles Bibliográficos
Autores principales: Saoji, Vikrant, Kulkarni, Sandeep, Madke, Bhushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830026/
https://www.ncbi.nlm.nih.gov/pubmed/31728106
http://dx.doi.org/10.4103/ijt.ijt_57_19
_version_ 1783465696013844480
author Saoji, Vikrant
Kulkarni, Sandeep
Madke, Bhushan
author_facet Saoji, Vikrant
Kulkarni, Sandeep
Madke, Bhushan
author_sort Saoji, Vikrant
collection PubMed
description Alopecia areata is commonly encountered non scarring alopecia with clinical presentations ranging from localised bald patches to extensive involvement. Clinical course is variable ranging from self limiting disease to chronic relapsing and recalcitrant disease. Topical and oral corticosteroids; nonetheless being front line agents for the treatment of alopecia areata;are not advocated for long term administration due to potentially undesirable systemic side effects. Hence the need of steroid sparing immunosuppresive agents like Azathioprine is warranted which have desired therapeutic action without much systemic adverse effects. We report a case series of 4 patients of alopecia areata treated with systemic azathioprine monotherapy.
format Online
Article
Text
id pubmed-6830026
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-68300262019-11-14 Alopecia Areata Treated with Oral Azathioprine: A Case Series Saoji, Vikrant Kulkarni, Sandeep Madke, Bhushan Int J Trichology Brief Communication Alopecia areata is commonly encountered non scarring alopecia with clinical presentations ranging from localised bald patches to extensive involvement. Clinical course is variable ranging from self limiting disease to chronic relapsing and recalcitrant disease. Topical and oral corticosteroids; nonetheless being front line agents for the treatment of alopecia areata;are not advocated for long term administration due to potentially undesirable systemic side effects. Hence the need of steroid sparing immunosuppresive agents like Azathioprine is warranted which have desired therapeutic action without much systemic adverse effects. We report a case series of 4 patients of alopecia areata treated with systemic azathioprine monotherapy. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6830026/ /pubmed/31728106 http://dx.doi.org/10.4103/ijt.ijt_57_19 Text en Copyright: © 2019 International Journal of Trichology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Brief Communication
Saoji, Vikrant
Kulkarni, Sandeep
Madke, Bhushan
Alopecia Areata Treated with Oral Azathioprine: A Case Series
title Alopecia Areata Treated with Oral Azathioprine: A Case Series
title_full Alopecia Areata Treated with Oral Azathioprine: A Case Series
title_fullStr Alopecia Areata Treated with Oral Azathioprine: A Case Series
title_full_unstemmed Alopecia Areata Treated with Oral Azathioprine: A Case Series
title_short Alopecia Areata Treated with Oral Azathioprine: A Case Series
title_sort alopecia areata treated with oral azathioprine: a case series
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830026/
https://www.ncbi.nlm.nih.gov/pubmed/31728106
http://dx.doi.org/10.4103/ijt.ijt_57_19
work_keys_str_mv AT saojivikrant alopeciaareatatreatedwithoralazathioprineacaseseries
AT kulkarnisandeep alopeciaareatatreatedwithoralazathioprineacaseseries
AT madkebhushan alopeciaareatatreatedwithoralazathioprineacaseseries