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Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies
Chaperone-mediated autophagy (CMA) ensures the selective degradation of cellular proteins endowed with a KFERQ-like motif by lysosomes. It is estimated that 30% of all cellular proteins can be directed to the lysosome for CMA degradation, but only a few substrates have been formally identified so fa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830112/ https://www.ncbi.nlm.nih.gov/pubmed/31623164 http://dx.doi.org/10.3390/cells8101260 |