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Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies

Chaperone-mediated autophagy (CMA) ensures the selective degradation of cellular proteins endowed with a KFERQ-like motif by lysosomes. It is estimated that 30% of all cellular proteins can be directed to the lysosome for CMA degradation, but only a few substrates have been formally identified so fa...

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Detalles Bibliográficos
Autores principales: Robert, Guillaume, Jacquel, Arnaud, Auberger, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830112/
https://www.ncbi.nlm.nih.gov/pubmed/31623164
http://dx.doi.org/10.3390/cells8101260

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