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A comparative study of single-particle cryo-EM with liquid-nitrogen and liquid-helium cooling
Radiation damage is the most fundamental limitation for achieving high resolution in electron cryo-microscopy (cryo-EM) of biological samples. The effects of radiation damage are reduced by liquid-helium cooling, although the use of liquid helium is more challenging than that of liquid nitrogen. To...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830223/ https://www.ncbi.nlm.nih.gov/pubmed/31709065 http://dx.doi.org/10.1107/S2052252519011503 |