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Multiplexed Competitive Screening of One-Bead-One-Component Combinatorial Libraries Using a ClonePix 2 Colony Sorter

Screening solid-phase combinatorial libraries of bioactive compounds against fluorescently labeled target biomolecules is an established technology in ligand and drug discovery. Rarely, however, do screening methods include comprehensive strategies—beyond mere library blocking and competitive screen...

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Detalles Bibliográficos
Autores principales: Lavoie, R. Ashton, di Fazio, Alice, Carbonell, Ruben G., Menegatti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830312/
https://www.ncbi.nlm.nih.gov/pubmed/31623061
http://dx.doi.org/10.3390/ijms20205119