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Multiplexed Competitive Screening of One-Bead-One-Component Combinatorial Libraries Using a ClonePix 2 Colony Sorter
Screening solid-phase combinatorial libraries of bioactive compounds against fluorescently labeled target biomolecules is an established technology in ligand and drug discovery. Rarely, however, do screening methods include comprehensive strategies—beyond mere library blocking and competitive screen...
Autores principales: | Lavoie, R. Ashton, di Fazio, Alice, Carbonell, Ruben G., Menegatti, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830312/ https://www.ncbi.nlm.nih.gov/pubmed/31623061 http://dx.doi.org/10.3390/ijms20205119 |
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