Cellular Processing of the ABCG2 Transporter—Potential Effects on Gout and Drug Metabolism

The human ABCG2 is an important plasma membrane multidrug transporter, involved in uric acid secretion, modulation of absorption of drugs, and in drug resistance of cancer cells. Variants of the ABCG2 transporter, affecting cellular processing and trafficking, have been shown to cause gout and incre...

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Detalles Bibliográficos
Autores principales: Mózner, Orsolya, Bartos, Zsuzsa, Zámbó, Boglárka, Homolya, László, Hegedűs, Tamás, Sarkadi, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830335/
https://www.ncbi.nlm.nih.gov/pubmed/31597297
http://dx.doi.org/10.3390/cells8101215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830335/
https://www.ncbi.nlm.nih.gov/pubmed/31597297
http://dx.doi.org/10.3390/cells8101215

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