Cargando…

CARF, As An Oncogene, Promotes Colorectal Cancer Stemness By Activating ERBB Signaling Pathway

INTRODUCTION: The role of CARF, a calcium-responsive transcription factor, in colorectal cancer initiation and development is still unknown. Here, we report that CARF promotes colorectal cancer stemness through ERBB signaling pathway. MATERIALS AND METHODS: Both colorectal cancer cell lines and prim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Weiyi, Cao, Zheng, Pang, Yanmin, Feng, Teng, Tian, Hongtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830361/ https://www.ncbi.nlm.nih.gov/pubmed/31802911 http://dx.doi.org/10.2147/OTT.S225733

Ejemplares similares

CARF promotes spermatogonial self-renewal and proliferation through Wnt signaling pathway
por: Cui, Wenhao, et al.
Publicado: (2020)

CARF activates beta-catenin/TCF signaling in the hepatocellular carcinoma
por: Fan, Xin, et al.
Publicado: (2016)

RF19 | PSUN344 Control of Androgen Signaling and Metastasis by CARF in Prostate Cancer
por: Hasan, Kamrul, et al.
Publicado: (2022)

Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity
por: He, Xiaoli, et al.
Publicado: (2017)

CARF and WYL domains: ligand-binding regulators of prokaryotic defense systems
por: Makarova, Kira S., et al.
Publicado: (2014)

Enzymatic properties of CARF-domain proteins in Synechocystis sp. PCC 6803
por: Ding, Jin, et al.
Publicado: (2022)

Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis
por: Hasan, Kamrul M., et al.
Publicado: (2023)

FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion
por: Benlimame, Naciba, et al.
Publicado: (2005)

Genome-Wide Identification of Calcium-Response Factor (CaRF) Binding Sites Predicts a Role in Regulation of Neuronal Signaling Pathways
por: Pfenning, Andreas R., et al.
Publicado: (2010)

Precision Medicine in Metastatic Colorectal Cancer: Targeting ERBB2 (HER-2) Oncogene
por: Torres-Jiménez, Javier, et al.
Publicado: (2022)

The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors
por: Steens, Jurre A., et al.
Publicado: (2022)

CARF enrichment promotes epithelial–mesenchymal transition via Wnt/β-catenin signaling: its clinical relevance and potential as a therapeutic target
por: Kalra, Rajkumar S., et al.
Publicado: (2018)

ErbB Family Signalling: A Paradigm for Oncogene Addiction and Personalized Oncology
por: Jacobi, Nico, et al.
Publicado: (2017)

Proliferation of Colorectal Cancer Is Promoted by Two Signaling Transduction Expression Patterns: ErbB2/ErbB3/AKT and MET/ErbB3/MAPK
por: Yao, Yong-Liang, et al.
Publicado: (2013)

Tumor suppressor activity of miR-451: Identification of CARF as a new target
por: Li, Ling, et al.
Publicado: (2018)

THU496 A Positive Relationship Exists Between CARF And AR In Prostate Cancer
por: Hasan, Kamrul M, et al.
Publicado: (2023)

Emerging Role of ERBB2 in Targeted Therapy for Metastatic Colorectal Cancer: Signaling Pathways to Therapeutic Strategies
por: Wang, Nannan, et al.
Publicado: (2022)

ERBB2 oncogenicity: ERBIN helps to perform the job
por: Mei, Lin, et al.
Publicado: (2015)

Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling
por: Bancovik, Jasna, et al.
Publicado: (2015)

Expression of oncogenes in thyroid tumours: coexpression of c-erbB2/neu and c-erbB.
por: Aasland, R., et al.
Publicado: (1988)

Aberrant methylation of ERBB pathway genes in sporadic colorectal cancer
por: Szmida, Elzbieta, et al.
Publicado: (2014)

Proto-oncogene c-erbB2 initiates rat primordial follicle growth via PKC and MAPK pathways
por: Li-Ping, Zheng, et al.
Publicado: (2010)

A New Set of ESTs from Chickpea (Cicer arietinum L.) Embryo Reveals Two Novel F-Box Genes, CarF-box_PP2 and CarF-box_LysM, with Potential Roles in Seed Development
por: Gupta, Shefali, et al.
Publicado: (2015)

Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer
por: Lemieux, E, et al.
Publicado: (2015)

erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification.
por: Colomer, R., et al.
Publicado: (1994)

CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization
por: Werr, Lisa, et al.
Publicado: (2022)

Oncogenic Ras triggers hyperproliferation and impairs polarized colonic morphogenesis by autocrine ErbB3 signaling
por: Möller, Yvonne, et al.
Publicado: (2016)

RNA binding protein CUGBP1 mediates the liver metastasis of colorectal cancer by regulating the ErbB signal pathway
por: Qi, Zhi-Peng, et al.
Publicado: (2021)

Soyasapogenol-A targets CARF and results in suppression of tumor growth and metastasis in p53 compromised cancer cells
por: Omar, Amr, et al.
Publicado: (2020)

SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation
por: Steens, Jurre A., et al.
Publicado: (2021)

Fine Mapping and Gene Analysis of restorer-of-fertility Gene CaRf(HZ) in Pepper (Capsicum annuum L.)
por: Nie, Zhixing, et al.
Publicado: (2022)

Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling
por: Wandinger, Sebastian K., et al.
Publicado: (2016)

DMBA promotes ErbB2-mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability
por: Ma, Zhikun, et al.
Publicado: (2018)

Plasmalogens and Photooxidative Stress Signaling in Myxobacteria, and How it Unmasked CarF/TMEM189 as the Δ1′-Desaturase PEDS1 for Human Plasmalogen Biosynthesis
por: Padmanabhan, S., et al.
Publicado: (2022)

ERBB3 binding protein 1 promotes the progression of malignant melanoma through activation of the Wnt/ β-catenin signaling pathway
por: Bao, Yanqiu, et al.
Publicado: (2022)

c-erbB-2 oncogene as a prognostic marker in breast cancer.
por: Perren, T. J.
Publicado: (1991)

Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma.
por: Gilbertson, R. J., et al.
Publicado: (1995)

ERBB family fusions are recurrent and actionable oncogenic targets across cancer types
por: Schubert, Laura, et al.
Publicado: (2023)

The chromodomain helicase CHD4 regulates ERBB2 signaling pathway and autophagy in ERBB2(+) breast cancer cells
por: D'Alesio, Carolina, et al.
Publicado: (2019)

GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway
por: Zhang, Xiao-Xin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fj1jpbast0thb0g94k2dv7481f