Cargando…

Co-Administration Of iRGD Enhances Tumor-Targeted Delivery And Anti-Tumor Effects Of Paclitaxel-Loaded PLGA Nanoparticles For Colorectal Cancer Treatment

BACKGROUND: Nanoparticles exhibit great promise for improving the solubility and tissue-specific distribution of chemotherapeutic agents; however, the passive and highly variable enhanced permeability and retention (EPR) effects observed in tumors frequently leads to insufficient delivery of nanodru...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Yi, Su, Tao, Shi, Qiuxiao, Feng, Yanru, Tao, Ze, Huang, Qiuxia, Li, Lan, Hu, Liqiang, Li, Shengfu, Tan, Hong, Liu, Shan, Yang, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830451/ https://www.ncbi.nlm.nih.gov/pubmed/31802868 http://dx.doi.org/10.2147/IJN.S219820

Ejemplares similares

iRGD Peptide as a Tumor-Penetrating Enhancer for Tumor-Targeted Drug Delivery
por: Kang, Sujin, et al.
Publicado: (2020)

MicroRNA-539-5p-Loaded PLGA Nanoparticles Grafted with iRGD as a Targeting Treatment for Choroidal Neovascularization
por: Alanazi, Jouri S., et al.
Publicado: (2022)

Dual Effect of Chemo-PDT with Tumor Targeting Nanoparticles Containing iRGD Peptide
por: Kim, Gye Lim, et al.
Publicado: (2023)

Combined Self-Assembled iRGD Polymersomes for Effective Targeted siRNA Anti-Tumor Therapy
por: Li, Dongying, et al.
Publicado: (2022)

Enhanced Therapeutic Efficacy of iRGD-Conjugated Crosslinked Multilayer Liposomes for Drug Delivery
por: Liu, Yarong, et al.
Publicado: (2013)

iRGD-modified lipid–polymer hybrid nanoparticles loaded with isoliquiritigenin to enhance anti-breast cancer effect and tumor-targeting ability
por: Gao, Fei, et al.
Publicado: (2017)

Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells
por: Zhang, Jinming, et al.
Publicado: (2017)

Remarkable Boron Delivery Of iRGD-Modified Polymeric Nanoparticles For Boron Neutron Capture Therapy
por: Chen, Jiejian, et al.
Publicado: (2019)

iRGD Tumor-Penetrating Peptide-Modified Nano-Delivery System Based on a Marine Sulfated Polysaccharide for Enhanced Anti-Tumor Efficiency Against Breast Cancer
por: Chen, Bowei, et al.
Publicado: (2022)

An iRGD Based Strategy to Study Electrochemically the Species Inside a Cell
por: Ning, Limin, et al.
Publicado: (2012)

Co-administration of iRGD with peptide HPRP-A1 to improve anticancer activity and membrane penetrability
por: Hu, Cuihua, et al.
Publicado: (2018)

The Antitumour Activity of a Curcumin and Piperine Loaded iRGD-Modified Liposome: In Vitro and In Vivo Evaluation
por: Wang, Yingzheng, et al.
Publicado: (2023)

An iRGD peptide conjugated heparin nanocarrier for gastric cancer therapy
por: Ai, Shichao, et al.
Publicado: (2018)

Tumor-penetration and antitumor efficacy of cetuximab are enhanced by co-administered iRGD in a murine model of human NSCLC
por: Zhang, Yang, et al.
Publicado: (2016)

Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus
por: Al-Zaher, Ahmed Abdullah, et al.
Publicado: (2018)

Co-Administration of iRGD with Sorafenib-Loaded Iron-Based Metal-Organic Framework as a Targeted Ferroptosis Agent for Liver Cancer Therapy
por: Liu, Xianchuang, et al.
Publicado: (2021)

Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency
por: Bian, Xinyu, et al.
Publicado: (2016)

Bifunctional iRGD-anti-CD3 enhances antitumor potency of T cells by facilitating tumor infiltration and T-cell activation
por: Zhou, Shujuan, et al.
Publicado: (2021)

Tumor Microenvironment-Responsive Polymeric iRGD and Doxorubicin Conjugates Reduce Spontaneous Lung Metastasis in an Orthotopic Breast Cancer Model
por: Peng, Zheng-Hong, et al.
Publicado: (2022)

sTRAIL-iRGD is a promising therapeutic agent for gastric cancer treatment
por: Huang, Ying, et al.
Publicado: (2017)

Antitumor Activity of Thermosensitive Hydrogels Packaging Gambogic Acid Nanoparticles and Tumor-Penetrating Peptide iRGD Against Gastric Cancer
por: Zhang, Dinghu, et al.
Publicado: (2020)

Treatment of pancreatic ductal adenocarcinoma with tumor antigen specific-targeted delivery of paclitaxel loaded PLGA nanoparticles
por: Wu, Shu-ta, et al.
Publicado: (2018)

A Novel Strategy to Improve the Therapeutic Efficacy of Gemcitabine for Non-Small Cell Lung Cancer by the Tumor-Penetrating Peptide iRGD
por: Zhang, Qing, et al.
Publicado: (2015)

GSH-responsive SN38 dimer-loaded shape-transformable nanoparticles with iRGD for enhancing chemo-photodynamic therapy
por: Lin, Congcong, et al.
Publicado: (2020)

Antitumor effect of iRGD-modified liposomes containing conjugated linoleic acid–paclitaxel (CLA-PTX) on B16-F10 melanoma
por: Du, Ruo, et al.
Publicado: (2014)

Coupling Gd-DTPA with a bispecific, recombinant protein anti-EGFR-iRGD complex improves tumor targeting in MRI
por: XIN, XIAOYAN, et al.
Publicado: (2016)

Development of iRGD-Modified Peptide Carriers for Suicide Gene Therapy of Uterine Leiomyoma
por: Egorova, Anna, et al.
Publicado: (2021)

Anticancer activity of Pseudomonas aeruginosa derived peptide with iRGD in colon cancer therapy
por: Yaghoubi, Atieh, et al.
Publicado: (2023)

iRGD-Targeted Peptide Nanoparticles for Anti-Angiogenic RNAi-Based Therapy of Endometriosis
por: Egorova, Anna, et al.
Publicado: (2023)

iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma
por: Dong, Yanbing, et al.
Publicado: (2023)

Correction: iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma
por: Dong, Yanbing, et al.
Publicado: (2023)

iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer
por: Ding, Naiqing, et al.
Publicado: (2019)

Improved Anticancer Effect of Recombinant Protein izTRAIL Combined with Sorafenib and Peptide iRGD
por: Fadeev, Roman, et al.
Publicado: (2019)

Molecular Imaging of Steroid-Induced Osteonecrosis of the Femoral Head through iRGD-Targeted Microbubbles
por: Zhao, Ping, et al.
Publicado: (2022)

Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles
por: D’Amore, Vincenzo Maria, et al.
Publicado: (2023)

A single nucleotide mutation drastically increases the expression of tumor-homing NGR-TNFα in the E. coli M15-pQE30 system by improving gene transcription
por: Chen, Jie, et al.
Publicado: (2021)

iRGD: A Promising Peptide for Cancer Imaging and a Potential Therapeutic Agent for Various Cancers
por: Zuo, Houdong
Publicado: (2019)

iRGD conjugated nimbolide liposomes protect against endotoxin induced acute respiratory distress syndrome
por: Pooladanda, Venkatesh, et al.
Publicado: (2021)

Paclitaxel-loaded PLGA microspheres with a novel morphology to facilitate drug delivery and antitumor efficiency
por: Zhang, Zongrui, et al.
Publicado: (2018)

DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma
por: Yagolovich, Anne V., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j7mepj04ip0icpcjk03p1liptt