Cargando…

Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration

Purpose Essential tremor (ET) is the most common movement disorder. In recent years, an increasing number of studies have shown that this disease also has a variety of non-motor findings and may be of a neurodegenerative nature. This study aimed to evaluate the olfactory bulb volume (OBV) and the ol...

Descripción completa

Detalles Bibliográficos
Autores principales: Altunisik, Erman, Baykan, Ali H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830855/
https://www.ncbi.nlm.nih.gov/pubmed/31754581
http://dx.doi.org/10.7759/cureus.5846
_version_ 1783465847131471872
author Altunisik, Erman
Baykan, Ali H
author_facet Altunisik, Erman
Baykan, Ali H
author_sort Altunisik, Erman
collection PubMed
description Purpose Essential tremor (ET) is the most common movement disorder. In recent years, an increasing number of studies have shown that this disease also has a variety of non-motor findings and may be of a neurodegenerative nature. This study aimed to evaluate the olfactory bulb volume (OBV) and the olfactory tract length (OTL) and to demonstrate possible neurodegeneration in ET patients using magnetic resonance imaging (MRI). Methods The study included 30 ET patients (mean age=29.53±11.82 years) and 30 healthy controls (mean age=30.00±11.68 years). In the cranial MRI examination of both groups, the right, left and total OBV values ​​were measured in mm(3) and the right and left OTL values ​​were calculated manually in mm. Results There was no significant difference between the patient and control groups in the measured OBV values, but the OTL value of the patient group was statistically significantly lower than the control group. Conclusion Our study showed that the olfactory system might be involved in ET cases. We think that olfactory dysfunction, one of the non-motor symptoms in ET, can be clearly elucidated through both anatomical and functional studies, to be conducted with larger patient groups.
format Online
Article
Text
id pubmed-6830855
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-68308552019-11-21 Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration Altunisik, Erman Baykan, Ali H Cureus Radiology Purpose Essential tremor (ET) is the most common movement disorder. In recent years, an increasing number of studies have shown that this disease also has a variety of non-motor findings and may be of a neurodegenerative nature. This study aimed to evaluate the olfactory bulb volume (OBV) and the olfactory tract length (OTL) and to demonstrate possible neurodegeneration in ET patients using magnetic resonance imaging (MRI). Methods The study included 30 ET patients (mean age=29.53±11.82 years) and 30 healthy controls (mean age=30.00±11.68 years). In the cranial MRI examination of both groups, the right, left and total OBV values ​​were measured in mm(3) and the right and left OTL values ​​were calculated manually in mm. Results There was no significant difference between the patient and control groups in the measured OBV values, but the OTL value of the patient group was statistically significantly lower than the control group. Conclusion Our study showed that the olfactory system might be involved in ET cases. We think that olfactory dysfunction, one of the non-motor symptoms in ET, can be clearly elucidated through both anatomical and functional studies, to be conducted with larger patient groups. Cureus 2019-10-06 /pmc/articles/PMC6830855/ /pubmed/31754581 http://dx.doi.org/10.7759/cureus.5846 Text en Copyright © 2019, Altunisik et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiology
Altunisik, Erman
Baykan, Ali H
Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration
title Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration
title_full Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration
title_fullStr Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration
title_full_unstemmed Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration
title_short Comparison of the Olfactory Bulb Volume and the Olfactory Tract Length Between Patients Diagnosed with Essential Tremor and Healthy Controls: Findings in Favor of Neurodegeneration
title_sort comparison of the olfactory bulb volume and the olfactory tract length between patients diagnosed with essential tremor and healthy controls: findings in favor of neurodegeneration
topic Radiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830855/
https://www.ncbi.nlm.nih.gov/pubmed/31754581
http://dx.doi.org/10.7759/cureus.5846
work_keys_str_mv AT altunisikerman comparisonoftheolfactorybulbvolumeandtheolfactorytractlengthbetweenpatientsdiagnosedwithessentialtremorandhealthycontrolsfindingsinfavorofneurodegeneration
AT baykanalih comparisonoftheolfactorybulbvolumeandtheolfactorytractlengthbetweenpatientsdiagnosedwithessentialtremorandhealthycontrolsfindingsinfavorofneurodegeneration