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Synergistic effect of phosphodiesterase 4 inhibitor and serum on migration of endotoxin-stimulated macrophages

Macrophage migration is an essential step in host defense against infection and wound healing. Elevation of cAMP by inhibiting phosphodiesterase 4 (PDE4), enzymes that specifically degrade cAMP, is known to suppress various inflammatory responses in activated macrophages, but the role of PDE4 in mac...

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Detalles Bibliográficos
Autores principales:	Yang, Jing-Xing, Hsiung, Te-Chih, Weng, Fu-Chun, Ding, Shiau-Li, Wu, Chin-Pyng, Conti, Marco, Chuang, Tsung-Hsien, Catherine Jin, S-L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830870/ https://www.ncbi.nlm.nih.gov/pubmed/30409089 http://dx.doi.org/10.1177/1753425918809155

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