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TLR agonist combinations that stimulate Th type I polarizing responses from human neonates
Each year millions of neonates die due to vaccine preventable infectious diseases. Our study seeks to develop novel neonatal vaccines and improve immunogenicity of early childhood vaccines by incorporating TLR agonist-adjuvant combinations that overcome the inherent neonatal Th2 bias and stimulate T...
Autores principales: | Surendran, Naveen, Simmons, Andrea, Pichichero, Michael E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830928/ https://www.ncbi.nlm.nih.gov/pubmed/29673285 http://dx.doi.org/10.1177/1753425918771178 |
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