Cargando…
Insulin-Independent Reversal of Type-1 Diabetes Following Transplantation of Adult Brown Adipose Tissue Supplemented With IGF-1
As our previous publications show, it is feasible to reverse type 1 diabetes (T1D) without insulin in multiple mouse models, through transplantation of embryonic brown adipose tissue (BAT) in the subcutaneous space. Embryonic BAT transplants result in rapid and long-lasting euglycemia accompanied by...
Autores principales: | Gunawardana, Subhadra C., Piston, David W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831116/ https://www.ncbi.nlm.nih.gov/pubmed/31773053 http://dx.doi.org/10.1097/TXD.0000000000000945 |
Ejemplares similares
-
Reversal of Type 1 Diabetes in Mice by Brown Adipose Tissue Transplant
por: Gunawardana, Subhadra C., et al.
Publicado: (2012) -
Therapeutic value of brown adipose tissue: Correcting metabolic disease through generating healthy fat
por: Gunawardana, Subhadra C.
Publicado: (2012) -
Amiloride derivatives enhance insulin release in pancreatic islets from diabetic mice
por: Gunawardana, Subhadra C, et al.
Publicado: (2005) -
Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH
por: Gunawardana, Subhadra C, et al.
Publicado: (2004) -
Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function
por: Boucher, Jeremie, et al.
Publicado: (2016)