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Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA
Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, is growing in incidence but treatment options remain limited, particularly for late stage disease. As liver cirrhosis is the principal risk state for HCC development, markers to detect early HCC within this patient population a...
Autores principales: | Hlady, Ryan A., Zhao, Xia, Pan, Xiaoyu, Yang, Ju Dong, Ahmed, Fowsiyo, Antwi, Samuel O., Giama, Nasra H., Patel, Tushar, Roberts, Lewis R., Liu, Chen, Robertson, Keith D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831291/ https://www.ncbi.nlm.nih.gov/pubmed/31695765 http://dx.doi.org/10.7150/thno.35573 |
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