Human iPSCs can be differentiated into notochordal cells that reduce intervertebral disc degeneration in a porcine model

Introduction: As many as 80% of the adult population experience back pain at some point in their lifetimes. Previous studies have indicated a link between back pain and intervertebral disc (IVD) degeneration. Despite decades of research, there is an urgent need for robust stem cell therapy targeting...

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Detalles Bibliográficos
Autores principales: Sheyn, Dmitriy, Ben-David, Shiran, Tawackoli, Wafa, Zhou, Zhengwei, Salehi, Khosrawdad, Bez, Maxim, De Mel, Sandra, Chan, Virginia, Roth, Joseph, Avalos, Pablo, Giaconi, Joseph C., Yameen, Haneen, Hazanov, Lena, Seliktar, Dror, Li, Debiao, Gazit, Dan, Gazit, Zulma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831475/
https://www.ncbi.nlm.nih.gov/pubmed/31695783
http://dx.doi.org/10.7150/thno.34898

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