Haploidentical Stem Cell Transplantation in Children With Hematological Malignancies Using αβ(+) T-Cell Receptor and CD19(+) Cell Depleted Grafts: High CD56(dim)/CD56(bright) NK Cell Ratio Early Following Transplantation Is Associated With Lower Relapse Incidence and Better Outcome

We prospectively analyzed outcomes of haploidentical hematopoietic stem cell transplantation using αβ(+) T-cell receptor/CD19(+) depleted grafts. Sixty-three transplantations were performed in 60 patients. Twenty-eight patients were diagnosed with acute lymphoblastic leukemia (ALL), 27 patients were...

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Detalles Bibliográficos
Autores principales: Diaz, Miguel A., Zubicaray, Josune, Molina, Blanca, Abad, Lorea, Castillo, Ana, Sebastian, Elena, Galvez, Eva, Ruiz, Julia, Vicario, Jose Luis, Ramirez, Manuel, Sevilla, Julian, González-Vicent, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831520/
https://www.ncbi.nlm.nih.gov/pubmed/31736949
http://dx.doi.org/10.3389/fimmu.2019.02504

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