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Effect of PGC1-beta ablation on myonuclear organisation

Skeletal muscle fibres are large, elongated multinucleated cells. Each nucleus within a myofibre is responsible for generating gene products for a finite volume of cytoplasm—the myonuclear domain (MND). Variation in MND sizes during atrophy, hypertrophy and disease states, are common. The factors th...

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Detalles Bibliográficos
Autores principales: Beedour, Ryan, Ross, Jacob A., Levy, Yotam, Ochala, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831542/
https://www.ncbi.nlm.nih.gov/pubmed/31485877
http://dx.doi.org/10.1007/s10974-019-09549-3

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