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Effect of PGC1-beta ablation on myonuclear organisation
Skeletal muscle fibres are large, elongated multinucleated cells. Each nucleus within a myofibre is responsible for generating gene products for a finite volume of cytoplasm—the myonuclear domain (MND). Variation in MND sizes during atrophy, hypertrophy and disease states, are common. The factors th...
Autores principales: | Beedour, Ryan, Ross, Jacob A., Levy, Yotam, Ochala, Julien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831542/ https://www.ncbi.nlm.nih.gov/pubmed/31485877 http://dx.doi.org/10.1007/s10974-019-09549-3 |
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