Inhibiting the LPS-induced enhancement of mEPSC frequency in superficial dorsal horn neurons may serve as an electrophysiological model for alleviating pain

Pain is a major primary health care problem. Emerging studies show that inhibition of spinal microglial activation reduces pain. However, the precise mechanisms by which microglial activation contributes to nociceptive synaptic transmission remain unclear. In this study, we measured spontaneous syna...

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Detalles Bibliográficos
Autores principales: Yang, Chin-Tsang, Hung, Shih-Ya, Hsu, Sheng-Feng, MacDonald, Iona, Lin, Jaung-Geng, Luo, Sih-Ting, Lin, Pei-Lin, Chen, Yi-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831605/
https://www.ncbi.nlm.nih.gov/pubmed/31690742
http://dx.doi.org/10.1038/s41598-019-52405-0

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