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Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study

Here in this study regarding the over expression of TP, which causes some physical, mental and socio problems like psoriasis, chronic inflammatory disease, tumor angiogenesis and rheumatoid arthritis etc. By this consideration, the inhibition of this enzyme is vital to secure life from serious threa...

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Detalles Bibliográficos
Autores principales:	Zaman, Khalid, Rahim, Fazal, Taha, Muhammad, Wadood, Abdul, Shah, Syed Adnan Ali, Ahmed, Qamar Uddin, Zakaria, Zainul Amiruddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831664/ https://www.ncbi.nlm.nih.gov/pubmed/31690793 http://dx.doi.org/10.1038/s41598-019-52100-0

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