Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis

The data in this article contain supporting information for the research manuscript entitled “Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients” by Lang et al. [1]. Momundo Artemisia annua extract and an acetonitrile fraction thereof induce apoptosi...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmiech, Michael, Lang, Sophia J., Syrovets, Tatiana, Simmet, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Pharmacology, Toxicology and Pharmaceutical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831675/
https://www.ncbi.nlm.nih.gov/pubmed/31700954
http://dx.doi.org/10.1016/j.dib.2019.104635
_version_ 1783466024238055424
author Schmiech, Michael
Lang, Sophia J.
Syrovets, Tatiana
Simmet, Thomas
author_facet Schmiech, Michael
Lang, Sophia J.
Syrovets, Tatiana
Simmet, Thomas
author_sort Schmiech, Michael
collection PubMed
description The data in this article contain supporting information for the research manuscript entitled “Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients” by Lang et al. [1]. Momundo Artemisia annua extract and an acetonitrile fraction thereof induce apoptosis in MDA-MB-231 triple negative breast cancer cells as shown by XTT viability assay and induction of the subG(0)/G(1) cell population by flow cytometric analysis. Furthermore, the HPLC-DAD method used to characterize the Artemisia annua herbal preparation as well as UHPLC-MS/MS method used to quantify the most abundant compounds in the extract and its validation are presented.
format Online
Article
Text
id pubmed-6831675
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-68316752019-11-07 Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis Schmiech, Michael Lang, Sophia J. Syrovets, Tatiana Simmet, Thomas Data Brief Pharmacology, Toxicology and Pharmaceutical Science The data in this article contain supporting information for the research manuscript entitled “Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients” by Lang et al. [1]. Momundo Artemisia annua extract and an acetonitrile fraction thereof induce apoptosis in MDA-MB-231 triple negative breast cancer cells as shown by XTT viability assay and induction of the subG(0)/G(1) cell population by flow cytometric analysis. Furthermore, the HPLC-DAD method used to characterize the Artemisia annua herbal preparation as well as UHPLC-MS/MS method used to quantify the most abundant compounds in the extract and its validation are presented. Elsevier 2019-10-15 /pmc/articles/PMC6831675/ /pubmed/31700954 http://dx.doi.org/10.1016/j.dib.2019.104635 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Pharmacology, Toxicology and Pharmaceutical Science
Schmiech, Michael
Lang, Sophia J.
Syrovets, Tatiana
Simmet, Thomas
Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis
title Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis
title_full Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis
title_fullStr Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis
title_full_unstemmed Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis
title_short Data on cytotoxic activity of an Artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis
title_sort data on cytotoxic activity of an artemisia annua herbal preparation and validation of the quantification method for active ingredient analysis
topic Pharmacology, Toxicology and Pharmaceutical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831675/
https://www.ncbi.nlm.nih.gov/pubmed/31700954
http://dx.doi.org/10.1016/j.dib.2019.104635
work_keys_str_mv AT schmiechmichael dataoncytotoxicactivityofanartemisiaannuaherbalpreparationandvalidationofthequantificationmethodforactiveingredientanalysis
AT langsophiaj dataoncytotoxicactivityofanartemisiaannuaherbalpreparationandvalidationofthequantificationmethodforactiveingredientanalysis
AT syrovetstatiana dataoncytotoxicactivityofanartemisiaannuaherbalpreparationandvalidationofthequantificationmethodforactiveingredientanalysis
AT simmetthomas dataoncytotoxicactivityofanartemisiaannuaherbalpreparationandvalidationofthequantificationmethodforactiveingredientanalysis

Ejemplares similares