Single-cell RNA-sequencing analysis of estrogen- and endocrine-disrupting chemical-induced reorganization of mouse mammary gland

Menopause is a critical window of susceptibility for its sensitivity to endocrine disrupting chemicals due to the decline of endogenous estrogen. Using a surgical menopausal (ovariectomized) mouse model, we assessed how mammary tissue was affected by both 17β-estradiol (E2) and polybrominated diphen...

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Detalles Bibliográficos
Autores principales: Kanaya, Noriko, Chang, Gregory, Wu, Xiwei, Saeki, Kohei, Bernal, Lauren, Shim, Hyun-Jeong, Wang, Jinhui, Warden, Charles, Yamamoto, Takuro, Li, Jay, Park, June-Soo, Synold, Timothy, Vonderfecht, Steve, Rakoff, Michele, Neuhausen, Susan L., Chen, Shiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831695/
https://www.ncbi.nlm.nih.gov/pubmed/31701034
http://dx.doi.org/10.1038/s42003-019-0618-9

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