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Highly Variable Pharmacokinetics of Tyramine in Humans and Polymorphisms in OCT1, CYP2D6, and MAO-A
Tyramine, formed by the decarboxylation of tyrosine, is a natural constituent of numerous food products. As an indirect sympathomimetic, it can have potentially dangerous hypertensive effects. In vitro data indicated that the pharmacokinetics of tyramine possibly depend on the organic cation transpo...
Autores principales: | Rafehi, Muhammad, Faltraco, Frank, Matthaei, Johannes, Prukop, Thomas, Jensen, Ole, Grytzmann, Aileen, Blome, Felix G., Berger, Ralf Günter, Krings, Ulrich, Vormfelde, Stefan V., Tzvetkov, Mladen V., Brockmöller, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831736/ https://www.ncbi.nlm.nih.gov/pubmed/31736764 http://dx.doi.org/10.3389/fphar.2019.01297 |
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