Rapamycin Attenuates High Glucose-Induced Inflammation Through Modulation of mTOR/NF-κB Pathways in Macrophages

Background: The NLRP3 inflammasome is one of the key contributors to impaired wound healing in diabetes. In this study, we assessed the role of rapamycin on high glucose-induced inflammation in THP-1-derived macrophages and investigated the underlying signaling mechanisms. Methods: THP-1-derived mac...

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Detalles Bibliográficos
Autores principales: Dai, Jiezhi, Jiang, Chaoyin, Chen, Hua, Chai, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831745/
https://www.ncbi.nlm.nih.gov/pubmed/31736762
http://dx.doi.org/10.3389/fphar.2019.01292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831745/
https://www.ncbi.nlm.nih.gov/pubmed/31736762
http://dx.doi.org/10.3389/fphar.2019.01292

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