Cargando…
Analysis of CA Content and CPSF6 Dependence of Early HIV-1 Replication Complexes in SupT1-R5 Cells
HIV-1 infects host cells by fusion at the plasma membrane, leading to cytoplasmic entry of the viral capsid encasing the genome and replication machinery. The capsid eventually needs to disassemble, but time and location of uncoating are not fully characterized and may vary depending on the host cel...
Autores principales: | Zila, Vojtech, Müller, Thorsten G., Laketa, Vibor, Müller, Barbara, Kräusslich, Hans-Georg |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831778/ https://www.ncbi.nlm.nih.gov/pubmed/31690677 http://dx.doi.org/10.1128/mBio.02501-19 |
Ejemplares similares
-
Direct Capsid Labeling of Infectious HIV-1 by Genetic Code Expansion Allows Detection of Largely Complete Nuclear Capsids and Suggests Nuclear Entry of HIV-1 Complexes via Common Routes
por: Schifferdecker, Sandra, et al.
Publicado: (2022) -
HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the nuclear pore complex
por: Bejarano, David Alejandro, et al.
Publicado: (2019) -
HIV-1 capsid is the key orchestrator of early viral replication
por: Zila, Vojtech, et al.
Publicado: (2021) -
HIV-1 uncoating by release of viral cDNA from capsid-like structures in the nucleus of infected cells
por: Müller, Thorsten G, et al.
Publicado: (2021) -
Synchronized HIV assembly by tunable PIP(2) changes reveals PIP(2) requirement for stable Gag anchoring
por: Mücksch, Frauke, et al.
Publicado: (2017)