Increased mitochondrial NADPH oxidase 4 (NOX4) expression in aging is a causative factor in aortic stiffening

Aging is characterized by increased aortic stiffness, an early, independent predictor and cause of cardiovascular disease. Oxidative stress from excess reactive oxygen species (ROS) production increases with age. Mitochondria and NADPH oxidases (NOXs) are two major sources of ROS in cardiovascular s...

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Detalles Bibliográficos
Autores principales: Canugovi, Chandrika, Stevenson, Mark D., Vendrov, Aleksandr E., Hayami, Takayuki, Robidoux, Jacques, Xiao, Han, Zhang, You-Yi, Eitzman, Daniel T., Runge, Marschall S., Madamanchi, Nageswara R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831838/
https://www.ncbi.nlm.nih.gov/pubmed/31419754
http://dx.doi.org/10.1016/j.redox.2019.101288

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