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Reserve Flux Capacity in the Pentose Phosphate Pathway by NADPH Binding Is Conserved across Kingdoms

All organisms evolved defense mechanisms to counteract oxidative stress and buildup of reactive oxygen species (ROS). To test whether a potentially conserved mechanism exists for the rapid response, we investigated immediate metabolic dynamics of Escherichia coli, yeast, and human dermal fibroblasts...

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Detalles Bibliográficos
Autores principales:	Christodoulou, Dimitris, Kuehne, Andreas, Estermann, Alexandra, Fuhrer, Tobias, Lang, Paul, Sauer, Uwe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831883/ https://www.ncbi.nlm.nih.gov/pubmed/31536961 http://dx.doi.org/10.1016/j.isci.2019.08.047

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