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Using MRI to measure in vivo free radical production and perfusion dynamics in a mouse model of elevated oxidative stress and neurogenic atrophy

Mitochondrial dysfunction, reactive oxygen species (ROS) and oxidative damage have been implicated to play a causative role in age-related skeletal muscle atrophy and weakness (i.e. sarcopenia). Mice lacking the superoxide scavenger CuZnSOD (Sod1(−/−)) exhibit high levels of oxygen-derived radicals...

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Detalles Bibliográficos
Autores principales:	Ahn, Bumsoo, Smith, Nataliya, Saunders, Debra, Ranjit, Rojina, Kneis, Parker, Towner, Rheal A., Van Remmen, Holly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831885/ https://www.ncbi.nlm.nih.gov/pubmed/31470261 http://dx.doi.org/10.1016/j.redox.2019.101308

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