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Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016

OBJECTIVE: To document the evolution and optimization of the Zika virus (ZIKV) disease surveillance system in southern Viet Nam in 2016 and to describe the characteristics of the identified ZIKV-positive cases. METHODS: We established a sentinel surveillance system to monitor ZIKV transmission in ei...

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Autores principales: Phan, Lan Trong, Luong, Quang Chan, Do, Thi Hong Hien, Chiu, Cindy H, Cao, Thang Minh, Nguyen, Thao Thi Thanh, Diep, Hai Thanh, Huynh, Thao Phuong, Nguyen, Dung Tri, Le, Nga Hong, Otsu, Satoko, Tran, Phu Dac, Nguyen, Thuong Vu, Kato, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Health Organization 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831960/
https://www.ncbi.nlm.nih.gov/pubmed/31720051
http://dx.doi.org/10.5365/wpsar.2018.9.2.014
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author Phan, Lan Trong
Luong, Quang Chan
Do, Thi Hong Hien
Chiu, Cindy H
Cao, Thang Minh
Nguyen, Thao Thi Thanh
Diep, Hai Thanh
Huynh, Thao Phuong
Nguyen, Dung Tri
Le, Nga Hong
Otsu, Satoko
Tran, Phu Dac
Nguyen, Thuong Vu
Kato, Masaya
author_facet Phan, Lan Trong
Luong, Quang Chan
Do, Thi Hong Hien
Chiu, Cindy H
Cao, Thang Minh
Nguyen, Thao Thi Thanh
Diep, Hai Thanh
Huynh, Thao Phuong
Nguyen, Dung Tri
Le, Nga Hong
Otsu, Satoko
Tran, Phu Dac
Nguyen, Thuong Vu
Kato, Masaya
author_sort Phan, Lan Trong
collection PubMed
description OBJECTIVE: To document the evolution and optimization of the Zika virus (ZIKV) disease surveillance system in southern Viet Nam in 2016 and to describe the characteristics of the identified ZIKV-positive cases. METHODS: We established a sentinel surveillance system to monitor ZIKV transmission in eight sites in eight provinces and expanded the system to 71 sites in 20 provinces in southern Viet Nam in 2016. Blood and urine samples from patients who met the case definition at the sentinel sites were tested for ZIKV using real-time reverse transcription polymerase chain reaction at the Pasteur Institute in Ho Chi Minh City (PI-HCMC). We conducted descriptive analysis and mapped the ZIKV-positive cases. RESULTS: In 2016, 2190 specimens from 20 provinces in southern Viet Nam were tested for ZIKV at PI-HCMC; 626 (28.6%), 484 (22.1%), 35 (1.6%) and 1045 (47.7%) tests were conducted in the first, second, third and fourth quarters of the year, respectively. Of these tested specimens, 214 (9.8%) were ZIKV positive with 212 (99.1%) identified in the fourth quarter. In the fourth quarter, the highest positivity rate was those in age groups 30–39 years (30.0%) and 40–59 years (31.6%). Of the 214 ZIKV-positive patients, 210 (98.1%) presented with rash, 194 (90.7%) with fever, 149 (69.6%) with muscle pain, 123 (57.5%) with joint pain and 66 (30.8%) with conjunctivitis. DISCUSSION: The surveillance system for ZIKV disease underwent several phases of optimization in 2016, guided by the most up-to-date local data. Here we demonstrate an adaptable surveillance system that detected ZIKV-positive cases in southern Viet Nam.
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spelling pubmed-68319602019-11-12 Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016 Phan, Lan Trong Luong, Quang Chan Do, Thi Hong Hien Chiu, Cindy H Cao, Thang Minh Nguyen, Thao Thi Thanh Diep, Hai Thanh Huynh, Thao Phuong Nguyen, Dung Tri Le, Nga Hong Otsu, Satoko Tran, Phu Dac Nguyen, Thuong Vu Kato, Masaya Western Pac Surveill Response J Non theme issue OBJECTIVE: To document the evolution and optimization of the Zika virus (ZIKV) disease surveillance system in southern Viet Nam in 2016 and to describe the characteristics of the identified ZIKV-positive cases. METHODS: We established a sentinel surveillance system to monitor ZIKV transmission in eight sites in eight provinces and expanded the system to 71 sites in 20 provinces in southern Viet Nam in 2016. Blood and urine samples from patients who met the case definition at the sentinel sites were tested for ZIKV using real-time reverse transcription polymerase chain reaction at the Pasteur Institute in Ho Chi Minh City (PI-HCMC). We conducted descriptive analysis and mapped the ZIKV-positive cases. RESULTS: In 2016, 2190 specimens from 20 provinces in southern Viet Nam were tested for ZIKV at PI-HCMC; 626 (28.6%), 484 (22.1%), 35 (1.6%) and 1045 (47.7%) tests were conducted in the first, second, third and fourth quarters of the year, respectively. Of these tested specimens, 214 (9.8%) were ZIKV positive with 212 (99.1%) identified in the fourth quarter. In the fourth quarter, the highest positivity rate was those in age groups 30–39 years (30.0%) and 40–59 years (31.6%). Of the 214 ZIKV-positive patients, 210 (98.1%) presented with rash, 194 (90.7%) with fever, 149 (69.6%) with muscle pain, 123 (57.5%) with joint pain and 66 (30.8%) with conjunctivitis. DISCUSSION: The surveillance system for ZIKV disease underwent several phases of optimization in 2016, guided by the most up-to-date local data. Here we demonstrate an adaptable surveillance system that detected ZIKV-positive cases in southern Viet Nam. World Health Organization 2019-05-14 /pmc/articles/PMC6831960/ /pubmed/31720051 http://dx.doi.org/10.5365/wpsar.2018.9.2.014 Text en (c) 2019 The authors; licensee World Health Organization. This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL.
spellingShingle Non theme issue
Phan, Lan Trong
Luong, Quang Chan
Do, Thi Hong Hien
Chiu, Cindy H
Cao, Thang Minh
Nguyen, Thao Thi Thanh
Diep, Hai Thanh
Huynh, Thao Phuong
Nguyen, Dung Tri
Le, Nga Hong
Otsu, Satoko
Tran, Phu Dac
Nguyen, Thuong Vu
Kato, Masaya
Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
title Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
title_full Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
title_fullStr Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
title_full_unstemmed Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
title_short Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
title_sort findings and lessons from establishing zika virus surveillance in southern viet nam, 2016
topic Non theme issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831960/
https://www.ncbi.nlm.nih.gov/pubmed/31720051
http://dx.doi.org/10.5365/wpsar.2018.9.2.014
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