Adenosquamous Carcinoma of the Pancreas

A 60-year-old woman presented to hospital with abdominal pain and massive weight loss. Imaging studies confirmed the presence of a tumor of the pancreas. Histologic analysis of the sampling performed by echoendoscopic ultrasound fine-needle aspiration found aspects evocative of adenosquamous carcino...

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Autores principales: Del Arco, Hélène, Chakiba-Brugère, Camille, Salabert, Laura, Béchade, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831966/
https://www.ncbi.nlm.nih.gov/pubmed/31723321
http://dx.doi.org/10.1177/1179554919886587
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author Del Arco, Hélène
Chakiba-Brugère, Camille
Salabert, Laura
Béchade, Dominique
author_facet Del Arco, Hélène
Chakiba-Brugère, Camille
Salabert, Laura
Béchade, Dominique
author_sort Del Arco, Hélène
collection PubMed
description A 60-year-old woman presented to hospital with abdominal pain and massive weight loss. Imaging studies confirmed the presence of a tumor of the pancreas. Histologic analysis of the sampling performed by echoendoscopic ultrasound fine-needle aspiration found aspects evocative of adenosquamous carcinoma. This case report highlights the difficulties of clinical pathologic diagnosis for these occasionally composite tumors. The patient underwent palliative chemotherapy based on platinum and 5-fluorouracil, followed by second-line chemotherapy with FOLFIRI after progression. Adenosquamous carcinoma of the pancreas remains a rare tumor with very poor prognosis and limited therapeutic options.
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spelling pubmed-68319662019-11-13 Adenosquamous Carcinoma of the Pancreas Del Arco, Hélène Chakiba-Brugère, Camille Salabert, Laura Béchade, Dominique Clin Med Insights Oncol Case Report A 60-year-old woman presented to hospital with abdominal pain and massive weight loss. Imaging studies confirmed the presence of a tumor of the pancreas. Histologic analysis of the sampling performed by echoendoscopic ultrasound fine-needle aspiration found aspects evocative of adenosquamous carcinoma. This case report highlights the difficulties of clinical pathologic diagnosis for these occasionally composite tumors. The patient underwent palliative chemotherapy based on platinum and 5-fluorouracil, followed by second-line chemotherapy with FOLFIRI after progression. Adenosquamous carcinoma of the pancreas remains a rare tumor with very poor prognosis and limited therapeutic options. SAGE Publications 2019-11-05 /pmc/articles/PMC6831966/ /pubmed/31723321 http://dx.doi.org/10.1177/1179554919886587 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Del Arco, Hélène
Chakiba-Brugère, Camille
Salabert, Laura
Béchade, Dominique
Adenosquamous Carcinoma of the Pancreas
title Adenosquamous Carcinoma of the Pancreas
title_full Adenosquamous Carcinoma of the Pancreas
title_fullStr Adenosquamous Carcinoma of the Pancreas
title_full_unstemmed Adenosquamous Carcinoma of the Pancreas
title_short Adenosquamous Carcinoma of the Pancreas
title_sort adenosquamous carcinoma of the pancreas
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6831966/
https://www.ncbi.nlm.nih.gov/pubmed/31723321
http://dx.doi.org/10.1177/1179554919886587
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AT chakibabrugerecamille adenosquamouscarcinomaofthepancreas
AT salabertlaura adenosquamouscarcinomaofthepancreas
AT bechadedominique adenosquamouscarcinomaofthepancreas

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